It looks like a successful Fourth Joint Sheffield Conference on Chemoinformatics is in prospect, since the conference is already fully booked with a waiting list drawn up. It will be held in The Octagon Centre, University of Sheffield, UK, from 18th to 20th June, 2007, under the aegis of The Chemical Structure Association Trust and the Molecular Graphics and Modelling Society. The Organising Committee consists of Dr Val Gillet, Dr John Holliday, Dr Eleanor Gardiner, and Professor Peter Willett (all from this Department), plus Peter Gedeck, Novartis (on behalf of the Molecular Graphics and Modelling Society) and David Wild, University of Indiana (on behalf of the Chemical Structure Association Trust). http://cisrg.shef.ac.uk/shef2007/