The Information School’s Chemoinformatics Research Group has released a paper which will help the European Medicines Agency to decide whether new orphan drugs should be granted licences. Evaluation and supervision of medicines throughout the European Union is the responsibility of the European Medicines Agency. One particular activity which the Agency is involved in is the licensing of orphan drugs – medicines which are designed to treat people with rare diseases. This activity is currently carried out by a panel of human experts. However the Chemoinformatics Research Group’s paper outlines computer techniques that could be used to help the panel in deciding whether or not a new orphan drug should be granted a licence. The paper (Franco, P., Porta, N., Holliday, J. D. & Willett, P. “The use of 2D fingerprint methods to support the assessment of structural similarity in orphan drug legislation” Journal of Cheminformatics , 6:5, 2014) ca...
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